A panelist discusses how CD4 counts serve as measures of immune system status that typically increase by about 200 in the first year of antiretroviral therapy. Although there can be laboratory ...

For decades, cancer immunotherapy has focused primarily on CD8 + cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

This study analyzed lung infections in immunocompromised patients admitted to the ICU and explored how different levels of CD4⁺T-cell depletion are associated with pathogen distribution and ...

Among women with HIV infection, both lower CD4 counts and higher HIV RNA viral load were associated with higher incidence rates of moderate and severe cervical dysplasia, carcinoma in situ, and ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with longer PFS, suggesting T-cell composition may serve as a biomarker to ...

CD4/CD8 T-cell ratios in the renal interstitium significantly mediate the association between peripheral blood CD4+/CD8+ T-cell ratios and lupus nephritis therapeutic outcomes. Peripheral and renal ...