All cellular life—from humans to bacteria—possesses two layers of immunity: innate and adaptive. Scientists have long ...

CRISPR’s promise of curing diseases hit a setback when researchers discovered that AZD7648, a molecule designed to improve precision, also caused catastrophic hidden damage to DNA. Instead of perfect ...

How the expression of Cas proteins in bacterial CRISPR-Cas immune system adapts to the constantly changing CRISPR structures and crRNA expression levels has been a long-standing unresolved question.

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published Jan 26, ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

**Note: the release below is a special early release from the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, Spain, 27-30 April). Please credit the ...

In an extraordinary 6,000-word guest editorial in the October 2024 issue of The CRISPR Journal (a sister journal of GEN, published by Mary Ann Liebert, Inc.), Fyodor Urnov, PhD, laid out the urgent ...

Like the human immune system, bacteria learn from past infections. CRISPR sequences—short snippets of DNA from previous viruses—guide destructive enzymes towards invading bacteriophages that express ...

Confluence Genetics today announced the launch of Cas-CLEAR™, Collaterally Enhanced Activated Ribonuclease, a new CRISPR technology plat ...

New research presented early ahead of this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, 27-30 April) from a team of researchers in the Netherlands ...