Cytokines function as pivotal messengers between the immune and neuroendocrine systems, coordinating responses to infection, stress and injury. Proinflammatory mediators such as interleukin-1, ...

Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases in mouse ...

Cytokine interaction networks drive immune function, but they are difficult to map and study. Not only are these networks complex, but they are built by molecules that typically exist in low ...

Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and ...

Constant exposure of cells to stressing agents, such as pathogens, may disturb an organism's normal functioning. To fight stress, cells have developed several coping mechanisms, including the ...

In the past four years, the pathogen responsible for Coronavirus Disease 2019 (COVID-19), SARS-CoV-2, has infected more than 770 million people and caused more than 6.9 million deaths worldwide. The ...

In the broadest sense, immunomodulators are drugs that adjust immune responses, for example, modulation of cytokine levels. Cytokines are signaling proteins responsible for the regulation of immune ...

Audio player for Talking Techniques podcast episode about cytokines, from therapeutics to diagnostics. Contains playback controls including play/pause button, timeline slider, and volume controls. In ...

Investigators identified 9 cytokines that can distinguish between disease relapse and remission in ANCA-associated vasculitis. Investigators have identified cytokines they believe are involved in the ...