Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of ...

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

The cells in human bodies are subject to both chemical and mechanical forces. But until recently, scientists have not understood much about how to manipulate the mechanical side of that equation. That ...

Researchers at Hospital for Special Surgery (HSS) have uncovered a critical link between the immune system in early life and ...

People need to sleep, and sleep deprivation can cause many changes in the brain. But we have a poor understanding of why sleep is so crucial. New research has examined a fruit fly model to assess how ...

Scientists at City of Hope have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

An international research team led jointly by the University Medical Center Göttingen (UMG), the University of Göttingen and ...

How our genes work together to build our cells, organs and bodies, and how mutations in many genes contribute to disease remain fundamental questions in genetics. Despite more than a century of ...

The regulatory division of the immune system is vital for its overall function. Immune T cells originate in the bone marrow and then travel to the thymus—a kind of biological police academy. 2 Here, ...

Scientists have discovered that cells can sense far beyond the surfaces they touch. While individual cancer cells can probe about 10 microns ahead by tugging on surrounding collagen fibers, clusters ...

Read on to understand how sickle-shaped red blood cells block blood vessels, trigger pain crises and may lead to organ damage ...