The itching, redness and swelling of an allergic reaction are caused by mast cells—the vigilant first responders of the immune system that spring into action with histamine-filled granules in response ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown that in mice mast cells function as a sensor ...

Histamine is a biogenic amine released predominantly by mast cells and basophils during immediate hypersensitivity reactions. Four receptor subtypes (H1–H4) mediate its diverse effects, with the H1 ...

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause ...

Is there really a mushroom that can help hay fever? The discovery dates back to ancient times.

Mastocytosis is a rare condition where an excessive amount of mast cells gather in the organs and tissues of the body. It can affect the skin, lymph nodes, bone marrow, and other organ systems. Mast ...

With the rising numbers of people who experience allergic-like conditions without knowing why, it has come into realisation ...