It is well known in physics and chemistry that equal charges repel each other, while opposite charges attract. It was long assumed that this principle also applies when enzymes – the biological ...

Living systems such as cells rely on membrane pores and channels to transport molecules, exchange signals, and organize ...

Researchers used DNA nanotechnology to build a synthetic membrane that mimics cell pores, enabling coordinated transport and ...

Weizmann Institute of Science-led researchers have unveiled a computational workflow that crafts enzymes exhibiting catalytic efficiencies surpassing 100,000 M −1 s −1, achieving performance ...

Using directed evolution, researchers have developed an enzyme that catalyses the formation of biaryl bonds (Nature 2022, DOI: 10.1038/s41586-021-04365-7). This new enzyme makes carbon-carbon bonds ...

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2. In doing so, they reveal the inner workings of insulin-regulated ...

Enzymes are amazing catalysts. These proteins are made of nothing more than a handful of Earth-abundant elements, and they promote a vast array of reactions, convert chemical energy to physical motion ...

The enzyme accelerates this reaction by 10 17 times, simply by positioning negative and positive charges in the active centre. Since the substrate contains a negatively charged group that is split off ...